Antibody afhankelijke versterking en Sendai  Virus  als een mogelijke vaccin  Vector

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De uitdagingen van de ontwikkeling van vaccins tegen Betacoronaviruses: Antibody afhankelijke versterking en Sendai  Virus  als een mogelijke vaccin  Vector

 

Om een ​​effectief en veilig vaccin tegen bètacoronavirussen te ontwerpen, is het noodzakelijk om hun evolutionair conservatieve antigene determinanten te gebruiken die de combinatie van sterke humorale en celgemedieerde immuunresponsen zullen opwekken. Het richten op dergelijke determinanten minimaliseert het risico van antilichaamafhankelijke versterking van virale infectie. Dit fenomeen werd waargenomen in dierproeven met experimentele vaccins tegen SARS-CoV-1 en MERS-CoV die waren ontwikkeld op foundation van geïnactiveerd coronavirus of vectorconstructen die het spike-eiwit (S) van het virion tot expressie brengen.

De substitutie en glycosylering van bepaalde aminozuren in de antigene determinanten van het S-eiwit, evenals de conformationele veranderingen, kunnen tot hetzelfde impact leiden in een nieuw experimenteel vaccin tegen SARS-CoV-2. Het gebruik van meer conservatieve structurele en aanvullende virale eiwitten voor de antigene determinanten van het vaccin zal dit probleem helpen voorkomen. Deze evaluation schetst benaderingen voor het ontwikkelen van vaccins tegen het nieuwe SARS-CoV-2-coronavirus die zijn gebaseerd op niet-pathogene virale vectoren.

Voor een efficiënte preventie van infecties veroorzaakt door respiratoire pathogenen is het vermogen van het vaccin om mucosale immuniteit in de luchtwegen te stimuleren belangrijk. Een dergelijk vaccin kan worden ontwikkeld met behulp van een niet-pathogene Sendai-virusvector, omdat het intranasaal kan worden toegediend en een mucosale immuunrespons kan induceren die de antivirale barrière in de luchtwegen versterkt en een betrouwbare bescherming biedt tegen infectie.

Detectie van mutaties in gyrB met behulp van denaturerende hogedrukvloeistofchromatografie ( DHPLC ) tussen Salmonella enterica serovar Typhi en Paratyphi A.

 

Fluorochinolonresistentie wordt gemedieerd door mutaties in het chinolonenresistentiebepalende gebied (QRDR) van de topoisomerasegenen. Denaturerende hogedrukvloeistofchromatografie (DHPLC) werd geëvalueerd voor de detectie van klinisch belangrijke mutaties in gyrB bij Salmonella.

 

Salmonella Typhi en S. Paratyphi A, gekarakteriseerd voor mutatie in QRDR van gyrA, parC en parE, werden onderzocht op mutatie in gyrB door DHPLC en gevalideerd door sequencing.

 

De DHPLC-analyse was in staat om de testmutant te onderscheiden van isolaten met wildtype gyrB en mutanten te onderscheiden van andere mutanten op foundation van piekprofiel en verschuiving in retentietijd. Er werden drie sequentievarianten gedetecteerd op codon 464 en er werd ook een nieuwe mutatie Ser→Thr gedetecteerd . gyrB-mutatie was geassocieerd met niet-klassieke chinolonresistentie (NALS-CIPDS) in 34 isolaten van alleen S. Typhi en was verschillend van klassieke chinolonresistentie geassocieerd met gyrA-mutaties (NALR-CIPDS).

 

Opstelling van een protocol voor moleculaire diagnose van β-thalassemie-mutaties in Tunesië met behulp van denaturerende high-performance vloeistofchromatografie ( DHPLC ).

 

ACHTERGROND

β-thalassemie is een van de meest voorkomende autosomaal recessieve aandoeningen wereldwijd . Het vertoont een grote moleculaire heterogeniteit als gevolg van meer dan 200 oorzakelijke mutaties in het β-globine-gen. In Tunesië vertegenwoordigt β- thalassemie de meest voorkomende monogene hemoglobinestoornis met 2,21% van de dragers.

 

Efficiënte en betrouwbare screeningsmethoden voor mutaties zijn essentieel om geschikte preventieprogramma’s voor risicoparen op te zetten. Het doel van de huidige studie is om een ​​efficiënte methode te ontwikkelen op foundation van de denaturerende hogedrukvloeistofchromatografie (DHPLC) waarbij het hele β-globinegen (HBB) wordt gescreend op mutaties die ongeveer 90% van het spectrum beslaan.

 

METHODEN

We hebben de validatie uitgevoerd van een DHPLC-assay voor directe genotypering van 11 bekende β-thalassemie-mutaties in de Tunesische bevolking.

 

RESULTATEN

De DHPLC-assay werd vastgesteld op foundation van de analyse van 62 gearchiveerde β-thalassemiemonsters die eerder waren gegenotypeerd en vervolgens werden gevalideerd met volledige overeenstemming op 50 exams met blinde gerandomiseerde monsters die eerder waren gegenotypeerd met DNA-sequencing en met 96% consistentie op 40 monsters als een prospectieve studie.

CONCLUSIES

In vergelijking met andere genotyperingstechnieken kan de DHPLC-methode voldoen aan de vereisten van directe genotypering van bekende β-thalassemie-mutaties in Tunesië en kan het worden toegepast als een krachtig hulpmiddel voor de genetische screening van prenatale en postnatale individuen.

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Rabbit Anti-Mouse LIF

103-PA05 100ug
EUR 240

Mouse LIF Protein

E40MOP1672 20ug
EUR 495

Mouse LIF Protein

E40MOP2026 20ug
EUR 495

Mouse LIF Protein

E40MOP2028 20ug
EUR 495

Recombinant Mouse LIF

Z200195 10 µg
EUR 85
Description: LIF is a multifunctional secreted glycoprotein that exists in both soluble and matrix-bound forms. It displays biologic activities ranging from the differentiation of myeloid leukemic cells into macrophage lineage to effects on bone metabolism, inflammation, neural development, embryogenesis, and the maintenance of implantation. It is now clear that LIF is related in both structure and mechanism of action to the interleukin IL-6 family of cytokines, which also includes IL-11, ciliary neurotrophic factor, oncostatin M, and cardiotrophin 1. The actions of these cytokines are mediated through specific cell-surface receptors that consist of a unique chain and the shared signal transducing subunit gp130.

Recombinant Mouse LIF

Z200197 100 µg
EUR 385
Description: LIF is a multifunctional secreted glycoprotein that exists in both soluble and matrix-bound forms. It displays biologic activities ranging from the differentiation of myeloid leukemic cells into macrophage lineage to effects on bone metabolism, inflammation, neural development, embryogenesis, and the maintenance of implantation. It is now clear that LIF is related in both structure and mechanism of action to the interleukin IL-6 family of cytokines, which also includes IL-11, ciliary neurotrophic factor, oncostatin M, and cardiotrophin 1. The actions of these cytokines are mediated through specific cell-surface receptors that consist of a unique chain and the shared signal transducing subunit gp130.

Recombinant Mouse LIF

Z200199 1.0 mg
EUR 1200
Description: LIF is a multifunctional secreted glycoprotein that exists in both soluble and matrix-bound forms. It displays biologic activities ranging from the differentiation of myeloid leukemic cells into macrophage lineage to effects on bone metabolism, inflammation, neural development, embryogenesis, and the maintenance of implantation (2). It is now clear that LIF is related in both structure and mechanism of action to the interleukin IL-6 family of cytokines, which also includes IL-11, ciliary neurotrophic factor, oncostatin M, and cardiotrophin 1 (2). The actions of these cytokines are mediated through specific cell-surface receptors that consist of a unique chain and the shared signal transducing subunit gp130.

Recombinant Mouse LIF

Z200485 100 µg
EUR 1500
Description: LIF is a multifunctional secreted glycoprotein that exists in both soluble and matrix-bound forms. It displays biologic activities ranging from the differentiation of myeloid leukemic cells into macrophage lineage to effects on bone metabolism, inflammation, neural development, embryogenesis, and the maintenance of implantation (2). It is now clear that LIF is related in both structure and mechanism of action to the interleukin IL-6 family of cytokines, which also includes IL-11, ciliary neurotrophic factor, oncostatin M, and cardiotrophin 1 (2). The actions of these cytokines are mediated through specific cell-surface receptors that consist of a unique chain and the shared signal transducing subunit gp130.

anti- LIF antibody

FNab09804 100µg
EUR 658.5
Description: Antibody raised against LIF

anti- LIF antibody

LSMab09804 100 ug
EUR 463.2

Mouse LIF ELISA Kit

E28L0650 96T
EUR 666.67

Mouse LIF ELISA Kit

EK5250 96 tests
EUR 599

Mouse LIF ELISA Kit

EML0014 96Tests
EUR 625.2

Rat Monoclonal anti-mouse LIF

mAP-0122 100ug
EUR 250

Sheep Polyclonal anti-mouse LIF

mAP-5260 50ug
EUR 400

Mouse LIF shRNA Plasmid

20-abx971321
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  • 150 µg
  • 300 µg

Mouse LIF Recombinant Protein

M30-007 10 µg
EUR 99.75
Description: Leukemia Inhibitory Factor also called LIF is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Human and mouse LIF exhibit a 78% identity in its amino acid sequence. Human LIF is as active on human cells as is it is on mouse cells, though mouse LIF is about 1000 fold less active on human cells, than human LIF. Recombinant mouse LIF produced in E. coli is a single, non-glycosylated, polypeptide chain containing 180 amino acids and having a molecular mass of 19.86 kDa.

Mouse LIF Recombinant Protein

M30-008 50 µg
EUR 246.75
Description: Leukemia Inhibitory Factor also called LIF is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Human and mouse LIF exhibit a 78% identity in its amino acid sequence. Human LIF is as active on human cells as is it is on mouse cells, though mouse LIF is about 1000 fold less active on human cells, than human LIF. Recombinant mouse LIF produced in E. coli is a single, non-glycosylated, polypeptide chain containing 180 amino acids and having a molecular mass of 19.86 kDa.

Recombinant Mouse LIF Protein

R01400-1 100ug/vial
EUR 352.8

Recombinant Mouse LIF Protein

PKSM041100-100ug 100ug
EUR 739
Description: Mouse

Recombinant Mouse LIF Protein

PKSM041100-20ug 20ug
EUR 249
Description: Mouse

Mouse LIF PicoKine ELISA Kit

EK0580 96 wells
EUR 510
Description: For quantitative detection of mouse LIF in cell culture supernates, serum and plasma (heparin, EDTA).

Anti-Human LIF Antibody

101-M553 100 µg
EUR 399
Description: Based on its helical structure, LIF (Leukemia Inhibitory Factor) is considered a member of the Interleukin-6 family of cytokines. Functionally, it has been implicated in a many physiological processes including development, hematopoiesis, bone metabolism, and inflammation. Some cell types known to express LIF include activated T cells, monocytes, astrocytes, osteoblasts, keratinocytes, regenerating skeletal muscle, mast cells, and fibroblasts.

Anti-Human LIF Antibody

102-PA05S 100 µg
EUR 126
Description: Leukemia Inhibitory Factor also called LIF is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Human and mouse LIF exhibit a 78% identity in its amino acid sequence. Human LIF is as active on human cells as is it is on mouse cells, though mouse LIF is about 1000 fold less active on human cells, than human LIF.

LIF mouse monoclonal antibody, clone 4F7.2

MO16101-100 100 µg Ask for price

LIF mouse monoclonal antibody, clone 2H2.2

MO16102-100 100 µg Ask for price

Lif ORF Vector (Mouse) (pORF)

ORF049145 1.0 ug DNA
EUR 607.2

Lif ORF Vector (Mouse) (pORF)

ORF049146 1.0 ug DNA
EUR 607.2

Rabbit Anti-Human LIF

102-PA05 100ug
EUR 240

LIF ELISA Kit (Mouse) (OKBB00760)

OKBB00760 96 Wells
EUR 606
Description: Description of target: Leukemia inhibitory factor, or LIF, is an interleukin 6 class cytokine that affects cell growth by inhibiting differentiation. When LIF levels drop, the cells differentiate. The LIF was mapped gene to 22q11-q12.2 by Southern analysis of a series of mouse/human somatic cell hybrids and by in situ hybridization to the chromosomes of 2 normal males and some individuals with chromosomal rearrangements. The gene maps between the Philadelphia translocation BCR1 and the breakpoint of the translocation in cell line GM2324 at 22q12.2. LIF derives its name from its ability to induce the terminal differentiation of myeloid leukemic cells, thus preventing their continued growth. Other properties attributed to the cytokine include: the growth promotion and cell differentiation of different types of target cells, influence on bone metabolism, cachexia, neural development, embryogenesis and inflammation.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: <10pg/ml

LIF, Mouse Recombinant , 1MIU/ml

L4500-001 1ml
EUR 406.8

LIF, Mouse Recombinant , 1MIU/ml

L4500-005 5x1ml
EUR 1431.6

LIF ELISA Kit (Mouse) (OKEH04045)

OKEH04045 96 Wells
EUR 652.8
Description: Description of target: LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.039 ng/mL

LIF, Mouse Recombinant , 10MIU/ml

L4501-001 1ml
EUR 1744.8

Nori® Mouse LIF ELISA Kit

GR117058 96-well
EUR 461

Mouse LIF Recombinant Protein Lyophilized

IMSLIFRLY5UG each
EUR 317
Description: Mouse LIF Recombinant Protein Lyophilized

Human CellExp? LIF, mouse recombinant

7268-10 each
EUR 444

Mouse LIF protein, C-His tag

PRP1126-100ug 100 μg
EUR 379
Description: Mouse LIF protein, C-His tag, expressed in E. coli

Mouse LIF protein, C-His tag

PRP1126-1mg 1 mg
EUR 2509
Description: Mouse LIF protein, C-His tag, expressed in E. coli

Mouse LIF protein, C-His tag

PRP1126-20ug 20 μg
EUR 149
Description: Mouse LIF protein, C-His tag, expressed in E. coli

Mouse LIF protein, C-His tag

PRP1126-5ug 5 μg
EUR 59
Description: Mouse LIF protein, C-His tag, expressed in E. coli

Leukemia Inhibitory Factor (LIF), mouse

PR16102 5 ug
EUR 522

Leukemia Inhibitory Factor (LIF), mouse

PR16102-B each
EUR 436.5

Lif (untagged) - Mouse leukemia inhibitory factor (Lif), transcript variant 1, (10ug)

MC208887 10 µg Ask for price

Lif (untagged) - Mouse leukemia inhibitory factor (Lif), transcript variant 2, (10ug)

MC208888 10 µg Ask for price

Recombinant Mouse Lif Protein, No Tag

E40MOP2217 20ug
EUR 495

Lif (GFP-tagged) - Mouse leukemia inhibitory factor (Lif) transcript variant 1, (10ug)

MG223120 10 µg Ask for price

Lif (GFP-tagged) - Mouse leukemia inhibitory factor (Lif) transcript variant 2, (10ug)

MG223901 10 µg Ask for price

Lif (Myc-DDK-tagged) - Mouse leukemia inhibitory factor (Lif), transcript variant 1

MR223120 10 µg Ask for price

Lif (Myc-DDK-tagged) - Mouse leukemia inhibitory factor (Lif), transcript variant 2

MR223901 10 µg Ask for price

OKBB00760-96W - LIF ELISA Kit (Mouse)

OKBB00760-96W 96wells
EUR 538

OKEH04045-96W - LIF ELISA Kit (Mouse)

OKEH04045-96W 96Wells
EUR 425

Lif sgRNA CRISPR Lentivector set (Mouse)

K3872501 3 x 1.0 ug
EUR 406.8

Sheep Polyclonal anti-human LIF

hAP-5294 50ug
EUR 400

Leukemia Inhibitory Factor (LIF) Polyclonal Antibody (Mouse)

4-PAA085Mu01
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  • 100ul
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Description: A Rabbit polyclonal antibody against Mouse Leukemia Inhibitory Factor (LIF)

LIF, Leukemia inhibitory factor, murine (mouse)

RC234-18 5ug
EUR 125.26

Mouse Leukemia Inhibitory Factor (LIF) Protein

20-abx067761
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  • 100 ug
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Mouse Leukemia Inhibitory Factor (LIF) Protein

abx262959-1mg 1 mg
EUR 3801.6

Mouse Leukemia Inhibitory Factor (LIF) Protein

abx262959-3x10g 3x10 µg
EUR 393.6

Mouse Leukemia Inhibitory Factor (LIF) Protein

abx262959-3x2g 3x2 µg
EUR 276

Mouse Leukemia Inhibitory Factor (LIF) Protein

abx067761-10g 10 µg
EUR 212.5

Mouse Leukemia Inhibitory Factor (LIF) Protein

abx067761-50g 50 µg
EUR 387.5

Mouse Leukemia Inhibitory Factor (LIF) Protein

abx067761-100g 100 µg
EUR 550

Mouse Leukemia Inhibitory Factor (LIF) Protein

abx262959-10mg 10 mg
EUR 325

Mouse Leukemia Inhibitory Factor (LIF) Protein

abx262959-25mg 25 mg
EUR 3287.5

Mouse Leukemia Inhibitory Factor (LIF) Protein

abx262959-5mg 5 mg
EUR 225

Mouse LIF Flow Cytometry Assay - Group 3

MX85121 96 Tests
EUR 270

Mouse LIF Protein, His Tag (MALS verified)

LIF-M5227 1mg
EUR 321
Description: Mouse LIF, His Tag (LIF-M5227) is expressed from human 293 cells (HEK293). It contains AA Ser 24 - Phe 203 (Accession # P09056-1).

Mouse LIF Protein, Tag Free (MALS verified)

LIF-M5219 20ug
EUR 2856.9
Description: Mouse LIF Protein, Tag Free (LIF-M5219) is expressed from human 293 cells (HEK293). It contains AA Ser 24 - Phe 203 (Accession # P09056-1).

LIF Antibody

6245-002mg 0.02 mg
EUR 206.18
Description: LIF Antibody: LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. LIF was initially recognized by its ability to induce terminal differentiation of myeloid leukemic cells. It is a member of the IL-6 cytokine superfamily and can be highly glycosylated. LIF signaling is transduced through the LIF-R/gp130 receptor complex, leading to the phosphorylation and activation of the JAK/STAT pathway. Recent evidence shows that LIF inhibits cardiomyogenesis in embryonic stem cells via STAT3 activation.

LIF Antibody

6245-01mg 0.1 mg
EUR 523.7
Description: LIF Antibody: LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. LIF was initially recognized by its ability to induce terminal differentiation of myeloid leukemic cells. It is a member of the IL-6 cytokine superfamily and can be highly glycosylated. LIF signaling is transduced through the LIF-R/gp130 receptor complex, leading to the phosphorylation and activation of the JAK/STAT pathway. Recent evidence shows that LIF inhibits cardiomyogenesis in embryonic stem cells via STAT3 activation.

LIF Antibody

25283-100ul 100ul
EUR 468

LIF Antibody

36950 100ul
EUR 319

LIF Antibody

36950-100ul 100ul
EUR 302.4

LIF Antibody

E036950 100μg/100μl
EUR 255
Description: Available in various conjugation types.

LIF Antibody

DF13730 100ul
EUR 420

LIF Antibody

DF13730-100ul 100ul
EUR 280

LIF Antibody

DF13730-200ul 200ul
EUR 350

LIF Antibody

E91288 100μg
EUR 255
Description: Available in various conjugation types.

LIF Antibody

E38PA4058 100ul
EUR 225
Description: Available in various conjugation types.

LIF Antibody

E315544 100ug/200ul
EUR 295
Description: Available in various conjugation types.

LIF antibody

70R-12299 100 ug
EUR 343
Description: Rabbit polyclonal LIF antibody

LIF antibody

70R-14100 100 ug
EUR 519
Description: Affinity purified Rabbit polyclonal LIF antibody

LIF Antibody

5216-100 each
EUR 379.2

LIF Antibody

5216-30T each
EUR 175.2

LIF antibody

70R-6230 50 ug
EUR 467
Description: Rabbit polyclonal LIF antibody

LIF antibody

70R-51295 100 ul
EUR 242
Description: Purified Polyclonal LIF antibody

LIF Antibody

1-CSB-PA004761
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  • 100ug
  • 50ug
Description: A polyclonal antibody against LIF. Recognizes LIF from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/20000

LIF Antibody

1-CSB-PA012928ESR2HU
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  • 100ul
  • 50ul
Description: A polyclonal antibody against LIF. Recognizes LIF from Human. This antibody is Unconjugated. Tested in the following application: ELISA

LIF Antibody

1-CSB-PA198481
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  • 100ul
  • 50ul
Description: A polyclonal antibody against LIF. Recognizes LIF from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:10000, IHC:1:25-1:100

LIF Antibody

GWB-MT498C 50ug Ask for price

LIF Antibody

F49998-0.08ML 0.08 ml
EUR 140.25
Description: LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface.

LIF Antibody

F49998-0.4ML 0.4 ml
EUR 322.15
Description: LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface.

LIF antibody

PAab09804 100 ug
EUR 463.2

LIF Antibody

R30639 100 ug
EUR 356.15
Description: LIF is a pleiotropic cytokine produced at the maternal-fetal interface which has been shown to play an essential role in implantation in mice. It is produced in high amounts by the human endometrium and the trophoblast itself, and its receptors are present on cytotrophoblast cells. LIF could thus play a role in modulating HLA-G production and immune tolerance at the maternal-fetal interface. The gene maps to 22q11-q12.2, between the Philadelphia translocation BCR gene and the breakpoint of the translocation in cell line GM2324 at 22q12.2.

LIF Antibody

R31467 100 ug
EUR 356.15
Description: LIF is a pleiotropic cytokine produced at the maternal-fetal interface which has been shown to play an essential role in implantation in mice. This gene is mapped to 22q11-q12.2, between the Philadelphia translocation BCR gene and the breakpoint of the translocation in cell line GM2324 at 22q12.2. LIF is produced in high amounts by the human endometrium and the trophoblast itself, and LIF receptors are present on cytotrophoblast cells. It could, thus, play a role in modulating HLA-G production and immune tolerance at the maternal-fetal interface.

LIF Antibody

R36251-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: Leukemia inhibitory factor

Recombinant Mouse Leukemia Inhibitory Factor/lIF

AP75318 1mg
EUR 3209

Recombinant Mouse Leukemia Inhibitory Factor/lIF

C690-10ug 10ug
EUR 175.2
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Mouse Leukemia Inhibitory Factor/lIF

C690-1mg 1mg
EUR 2739.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Mouse Leukemia Inhibitory Factor/lIF

C690-500ug 500ug
EUR 1935.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Mouse Leukemia Inhibitory Factor/lIF

C690-50ug 50ug
EUR 363.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

LIF Protein Vector (Mouse) (pPM-C-HA)

PV196580 500 ng
EUR 723.6

LIF Protein Vector (Mouse) (pPM-C-HA)

PV196584 500 ng
EUR 723.6

LIF

cyt-644 5µg
EUR 60
Description: Recombinant Human Leukemia Inhibitory Factor

LIF

E8ER1912-32 100ul
EUR 275
Description: Available in various conjugation types.

Ontwikkeling van hoge resolutie DNA Melting Analyse voor gelijktijdige detectie van Potato Mop-Prime  Virus  en Zijn  Vector , Spongospora subterranea, in de bodem 

In deze studie werd een reeks duplex reverse transcriptie (RT)-PCR-gemedieerde hoge resolutie DNA-smelt (HRM)-analyses voor gelijktijdige detectie van aardappelmop-virus (PMTV) en zijn protistische vector, Spongospora subterranea f.sp. subterranea (Sss), ontwikkeld.

De aantasting van grond door PMTV werd gedetecteerd met behulp van een op tabak gebaseerd lokaassysteem . Totaal RNA geëxtraheerd uit de bodem leidde tot succesvolle RT-PCR-gelelektroforese-detectie van zowel PMTV als Sss. Om efficiëntere detectie te vergemakkelijken, werden nieuw ontworpen primerparen voor PMTV RNA-soorten (dwz RNA-Rep, -CP en -TGB) samen met de bestaande Sss-primers geanalyseerd met behulp van real-time RT-PCR.

De resulterende amplicons vertoonden smeltprofielen die gemakkelijk konden worden onderscheiden. Onder duplex RT-PCR-formaat leidden alle PMTV- en Sss-primercombinaties tot succesvolle detectie van respectieve PMTV-RNA-soorten en Sss in de monsters door DNA- smeltanalyses met hoge resolutie (HRM) . Toen de duplex HRM-assay werd toegepast op bodemmonsters die waren verzameld van zes velden op vier verschillende locaties in New Brunswick, Canada, werd een positieve detectie van PMTV en/of Sss gevonden in 63-100% monsters verzameld uit velden waarin met PMTV geïnfecteerde knollen waren waargenomen.

De monsters van velden waar noch PMTV- noch Sss-geïnfecteerde knollen waren waargenomen, resulteerden daarentegen in een negatieve detectie door de check. Aastabak bioassay voor PMTV en Sss leverde vergelijkbare resultaten op. Tussen 63% -83% en 100% van de grondmonsters die werden verzameld op PMTV-besmette velden leidden tot respectievelijk PMTV- en Sss-infecties in de lokaasplanten; terwijl er geen PMTV- of Sss-geïnfecteerde planten werden verkregen uit grondmonsters die waren verzameld op PMTV/Sss-vrije velden.

Versnelling van de morfogenetische cyclus van de  virale  vector  Aedes aegypti  larven voor snellere larvicide bioassays

 

Elke bioassay om nieuwe chemisch gesynthetiseerde larviciden of fytolarviciden te testen tegen Culicidae  en meer schadelijke muggensoorten, zoals  Aede s  aegypti  en  Aedes albopictus , die specifiek knokkelkoorts, gele koorts, chikungunya- viruskoorts  overbrengen, evenals het Zika-virus of  Anopheles gambiae , een vector voor malaria en philariasis, vereist duizenden goed ontwikkelde larven, bij voorkeur in het vierde stadium. De natuurlijke morfogenetische cyclus van  Aedes  spp., in het veld of in het laboratorium, kan bij kamertemperatuur (bijv. 25°C) tot 19 dagen duren vanaf het eerste permanente contact tussen levensvatbare eieren en wateren het laatste stadium van larvale groei of metamorfose tot vliegende volwassenen. Een versnelde sequentiële vervelling is dus wenselijk voor snellere bioassays van larviciden.

We hebben dit doel bereikt in  Aedes aegypti  met zeer beperkte strategische en goedkope toevoegingen aan voedsel, zoals kokoswater, melk of caseïne, gistextract en in mindere mate glycerol. Het van nature rijke kokoswater was uitstekend geschikt om snel de populatie van instar IV-larven te bereiken , de meest geavanceerde vóór de verpopping, wat ongeveer een week bespaart voor daaropvolgende larvicide bioassays. Verdunde melk, als een andere voedselbron, zorgde voor een nog snellere uiteindelijke vervelling en volwassenen zijn nuttig voor taxonomische doeleinden van muggen.

Rabbit Anti-Mouse LIF

103-PA05 100ug
EUR 240

Mouse LIF Protein

E40MOP1672 20ug
EUR 495

Mouse LIF Protein

E40MOP2026 20ug
EUR 495

Mouse LIF Protein

E40MOP2028 20ug
EUR 495

Recombinant Mouse LIF

Z200195 10 µg
EUR 85
Description: LIF is a multifunctional secreted glycoprotein that exists in both soluble and matrix-bound forms. It displays biologic activities ranging from the differentiation of myeloid leukemic cells into macrophage lineage to effects on bone metabolism, inflammation, neural development, embryogenesis, and the maintenance of implantation. It is now clear that LIF is related in both structure and mechanism of action to the interleukin IL-6 family of cytokines, which also includes IL-11, ciliary neurotrophic factor, oncostatin M, and cardiotrophin 1. The actions of these cytokines are mediated through specific cell-surface receptors that consist of a unique chain and the shared signal transducing subunit gp130.

Recombinant Mouse LIF

Z200197 100 µg
EUR 385
Description: LIF is a multifunctional secreted glycoprotein that exists in both soluble and matrix-bound forms. It displays biologic activities ranging from the differentiation of myeloid leukemic cells into macrophage lineage to effects on bone metabolism, inflammation, neural development, embryogenesis, and the maintenance of implantation. It is now clear that LIF is related in both structure and mechanism of action to the interleukin IL-6 family of cytokines, which also includes IL-11, ciliary neurotrophic factor, oncostatin M, and cardiotrophin 1. The actions of these cytokines are mediated through specific cell-surface receptors that consist of a unique chain and the shared signal transducing subunit gp130.

Recombinant Mouse LIF

Z200199 1.0 mg
EUR 1200
Description: LIF is a multifunctional secreted glycoprotein that exists in both soluble and matrix-bound forms. It displays biologic activities ranging from the differentiation of myeloid leukemic cells into macrophage lineage to effects on bone metabolism, inflammation, neural development, embryogenesis, and the maintenance of implantation (2). It is now clear that LIF is related in both structure and mechanism of action to the interleukin IL-6 family of cytokines, which also includes IL-11, ciliary neurotrophic factor, oncostatin M, and cardiotrophin 1 (2). The actions of these cytokines are mediated through specific cell-surface receptors that consist of a unique chain and the shared signal transducing subunit gp130.

Recombinant Mouse LIF

Z200485 100 µg
EUR 1500
Description: LIF is a multifunctional secreted glycoprotein that exists in both soluble and matrix-bound forms. It displays biologic activities ranging from the differentiation of myeloid leukemic cells into macrophage lineage to effects on bone metabolism, inflammation, neural development, embryogenesis, and the maintenance of implantation (2). It is now clear that LIF is related in both structure and mechanism of action to the interleukin IL-6 family of cytokines, which also includes IL-11, ciliary neurotrophic factor, oncostatin M, and cardiotrophin 1 (2). The actions of these cytokines are mediated through specific cell-surface receptors that consist of a unique chain and the shared signal transducing subunit gp130.

anti- LIF antibody

FNab09804 100µg
EUR 658.5
Description: Antibody raised against LIF

anti- LIF antibody

LSMab09804 100 ug
EUR 463.2

Mouse LIF ELISA Kit

E28L0650 96T
EUR 666.67

Mouse LIF ELISA Kit

EK5250 96 tests
EUR 599

Mouse LIF ELISA Kit

EML0014 96Tests
EUR 625.2

Rat Monoclonal anti-mouse LIF

mAP-0122 100ug
EUR 250

Sheep Polyclonal anti-mouse LIF

mAP-5260 50ug
EUR 400

Mouse LIF shRNA Plasmid

20-abx971321
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  • 150 µg
  • 300 µg

Mouse LIF Recombinant Protein

M30-007 10 µg
EUR 99.75
Description: Leukemia Inhibitory Factor also called LIF is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Human and mouse LIF exhibit a 78% identity in its amino acid sequence. Human LIF is as active on human cells as is it is on mouse cells, though mouse LIF is about 1000 fold less active on human cells, than human LIF. Recombinant mouse LIF produced in E. coli is a single, non-glycosylated, polypeptide chain containing 180 amino acids and having a molecular mass of 19.86 kDa.

Mouse LIF Recombinant Protein

M30-008 50 µg
EUR 246.75
Description: Leukemia Inhibitory Factor also called LIF is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Human and mouse LIF exhibit a 78% identity in its amino acid sequence. Human LIF is as active on human cells as is it is on mouse cells, though mouse LIF is about 1000 fold less active on human cells, than human LIF. Recombinant mouse LIF produced in E. coli is a single, non-glycosylated, polypeptide chain containing 180 amino acids and having a molecular mass of 19.86 kDa.

Recombinant Mouse LIF Protein

R01400-1 100ug/vial
EUR 352.8

Recombinant Mouse LIF Protein

PKSM041100-100ug 100ug
EUR 739
Description: Mouse

Recombinant Mouse LIF Protein

PKSM041100-20ug 20ug
EUR 249
Description: Mouse

Mouse LIF PicoKine ELISA Kit

EK0580 96 wells
EUR 510
Description: For quantitative detection of mouse LIF in cell culture supernates, serum and plasma (heparin, EDTA).

Anti-Human LIF Antibody

101-M553 100 µg
EUR 399
Description: Based on its helical structure, LIF (Leukemia Inhibitory Factor) is considered a member of the Interleukin-6 family of cytokines. Functionally, it has been implicated in a many physiological processes including development, hematopoiesis, bone metabolism, and inflammation. Some cell types known to express LIF include activated T cells, monocytes, astrocytes, osteoblasts, keratinocytes, regenerating skeletal muscle, mast cells, and fibroblasts.

Anti-Human LIF Antibody

102-PA05S 100 µg
EUR 126
Description: Leukemia Inhibitory Factor also called LIF is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Human and mouse LIF exhibit a 78% identity in its amino acid sequence. Human LIF is as active on human cells as is it is on mouse cells, though mouse LIF is about 1000 fold less active on human cells, than human LIF.

LIF mouse monoclonal antibody, clone 4F7.2

MO16101-100 100 µg Ask for price

LIF mouse monoclonal antibody, clone 2H2.2

MO16102-100 100 µg Ask for price

Lif ORF Vector (Mouse) (pORF)

ORF049145 1.0 ug DNA
EUR 607.2

Lif ORF Vector (Mouse) (pORF)

ORF049146 1.0 ug DNA
EUR 607.2

Rabbit Anti-Human LIF

102-PA05 100ug
EUR 240

LIF ELISA Kit (Mouse) (OKBB00760)

OKBB00760 96 Wells
EUR 606
Description: Description of target: Leukemia inhibitory factor, or LIF, is an interleukin 6 class cytokine that affects cell growth by inhibiting differentiation. When LIF levels drop, the cells differentiate. The LIF was mapped gene to 22q11-q12.2 by Southern analysis of a series of mouse/human somatic cell hybrids and by in situ hybridization to the chromosomes of 2 normal males and some individuals with chromosomal rearrangements. The gene maps between the Philadelphia translocation BCR1 and the breakpoint of the translocation in cell line GM2324 at 22q12.2. LIF derives its name from its ability to induce the terminal differentiation of myeloid leukemic cells, thus preventing their continued growth. Other properties attributed to the cytokine include: the growth promotion and cell differentiation of different types of target cells, influence on bone metabolism, cachexia, neural development, embryogenesis and inflammation.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: <10pg/ml

LIF, Mouse Recombinant , 1MIU/ml

L4500-001 1ml
EUR 406.8

LIF, Mouse Recombinant , 1MIU/ml

L4500-005 5x1ml
EUR 1431.6

LIF ELISA Kit (Mouse) (OKEH04045)

OKEH04045 96 Wells
EUR 652.8
Description: Description of target: LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.039 ng/mL

LIF, Mouse Recombinant , 10MIU/ml

L4501-001 1ml
EUR 1744.8

Nori® Mouse LIF ELISA Kit

GR117058 96-well
EUR 461

Mouse LIF Recombinant Protein Lyophilized

IMSLIFRLY5UG each
EUR 317
Description: Mouse LIF Recombinant Protein Lyophilized

Human CellExp? LIF, mouse recombinant

7268-10 each
EUR 444

Mouse LIF protein, C-His tag

PRP1126-100ug 100 μg
EUR 379
Description: Mouse LIF protein, C-His tag, expressed in E. coli

Mouse LIF protein, C-His tag

PRP1126-1mg 1 mg
EUR 2509
Description: Mouse LIF protein, C-His tag, expressed in E. coli

Mouse LIF protein, C-His tag

PRP1126-20ug 20 μg
EUR 149
Description: Mouse LIF protein, C-His tag, expressed in E. coli

Mouse LIF protein, C-His tag

PRP1126-5ug 5 μg
EUR 59
Description: Mouse LIF protein, C-His tag, expressed in E. coli

Leukemia Inhibitory Factor (LIF), mouse

PR16102 5 ug
EUR 522

Leukemia Inhibitory Factor (LIF), mouse

PR16102-B each
EUR 436.5

Lif (untagged) - Mouse leukemia inhibitory factor (Lif), transcript variant 1, (10ug)

MC208887 10 µg Ask for price

Lif (untagged) - Mouse leukemia inhibitory factor (Lif), transcript variant 2, (10ug)

MC208888 10 µg Ask for price

Recombinant Mouse Lif Protein, No Tag

E40MOP2217 20ug
EUR 495

Lif (GFP-tagged) - Mouse leukemia inhibitory factor (Lif) transcript variant 1, (10ug)

MG223120 10 µg Ask for price

Lif (GFP-tagged) - Mouse leukemia inhibitory factor (Lif) transcript variant 2, (10ug)

MG223901 10 µg Ask for price

Lif (Myc-DDK-tagged) - Mouse leukemia inhibitory factor (Lif), transcript variant 1

MR223120 10 µg Ask for price

Lif (Myc-DDK-tagged) - Mouse leukemia inhibitory factor (Lif), transcript variant 2

MR223901 10 µg Ask for price

OKBB00760-96W - LIF ELISA Kit (Mouse)

OKBB00760-96W 96wells
EUR 538

OKEH04045-96W - LIF ELISA Kit (Mouse)

OKEH04045-96W 96Wells
EUR 425

Lif sgRNA CRISPR Lentivector set (Mouse)

K3872501 3 x 1.0 ug
EUR 406.8

Sheep Polyclonal anti-human LIF

hAP-5294 50ug
EUR 400

Leukemia Inhibitory Factor (LIF) Polyclonal Antibody (Mouse)

4-PAA085Mu01
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Leukemia Inhibitory Factor (LIF)

LIF, Leukemia inhibitory factor, murine (mouse)

RC234-18 5ug
EUR 125.26

Mouse Leukemia Inhibitory Factor (LIF) Protein

20-abx067761
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Leukemia Inhibitory Factor (LIF) Protein

abx262959-1mg 1 mg
EUR 3801.6

Mouse Leukemia Inhibitory Factor (LIF) Protein

abx262959-3x10g 3x10 µg
EUR 393.6

Mouse Leukemia Inhibitory Factor (LIF) Protein

abx262959-3x2g 3x2 µg
EUR 276

Mouse Leukemia Inhibitory Factor (LIF) Protein

abx067761-10g 10 µg
EUR 212.5

Mouse Leukemia Inhibitory Factor (LIF) Protein

abx067761-50g 50 µg
EUR 387.5

Mouse Leukemia Inhibitory Factor (LIF) Protein

abx067761-100g 100 µg
EUR 550

Mouse Leukemia Inhibitory Factor (LIF) Protein

abx262959-10mg 10 mg
EUR 325

Mouse Leukemia Inhibitory Factor (LIF) Protein

abx262959-25mg 25 mg
EUR 3287.5

Mouse Leukemia Inhibitory Factor (LIF) Protein

abx262959-5mg 5 mg
EUR 225

Mouse LIF Flow Cytometry Assay - Group 3

MX85121 96 Tests
EUR 270

Mouse LIF Protein, His Tag (MALS verified)

LIF-M5227 1mg
EUR 321
Description: Mouse LIF, His Tag (LIF-M5227) is expressed from human 293 cells (HEK293). It contains AA Ser 24 - Phe 203 (Accession # P09056-1).

Mouse LIF Protein, Tag Free (MALS verified)

LIF-M5219 20ug
EUR 2856.9
Description: Mouse LIF Protein, Tag Free (LIF-M5219) is expressed from human 293 cells (HEK293). It contains AA Ser 24 - Phe 203 (Accession # P09056-1).

LIF Antibody

6245-002mg 0.02 mg
EUR 206.18
Description: LIF Antibody: LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. LIF was initially recognized by its ability to induce terminal differentiation of myeloid leukemic cells. It is a member of the IL-6 cytokine superfamily and can be highly glycosylated. LIF signaling is transduced through the LIF-R/gp130 receptor complex, leading to the phosphorylation and activation of the JAK/STAT pathway. Recent evidence shows that LIF inhibits cardiomyogenesis in embryonic stem cells via STAT3 activation.

LIF Antibody

6245-01mg 0.1 mg
EUR 523.7
Description: LIF Antibody: LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. LIF was initially recognized by its ability to induce terminal differentiation of myeloid leukemic cells. It is a member of the IL-6 cytokine superfamily and can be highly glycosylated. LIF signaling is transduced through the LIF-R/gp130 receptor complex, leading to the phosphorylation and activation of the JAK/STAT pathway. Recent evidence shows that LIF inhibits cardiomyogenesis in embryonic stem cells via STAT3 activation.

LIF Antibody

25283-100ul 100ul
EUR 468

LIF Antibody

36950 100ul
EUR 319

LIF Antibody

36950-100ul 100ul
EUR 302.4

LIF Antibody

E036950 100μg/100μl
EUR 255
Description: Available in various conjugation types.

LIF Antibody

DF13730 100ul
EUR 420

LIF Antibody

DF13730-100ul 100ul
EUR 280

LIF Antibody

DF13730-200ul 200ul
EUR 350

LIF Antibody

E91288 100μg
EUR 255
Description: Available in various conjugation types.

LIF Antibody

E38PA4058 100ul
EUR 225
Description: Available in various conjugation types.

LIF Antibody

E315544 100ug/200ul
EUR 295
Description: Available in various conjugation types.

LIF antibody

70R-12299 100 ug
EUR 343
Description: Rabbit polyclonal LIF antibody

LIF antibody

70R-14100 100 ug
EUR 519
Description: Affinity purified Rabbit polyclonal LIF antibody

LIF Antibody

5216-100 each
EUR 379.2

LIF Antibody

5216-30T each
EUR 175.2

LIF antibody

70R-6230 50 ug
EUR 467
Description: Rabbit polyclonal LIF antibody

LIF antibody

70R-51295 100 ul
EUR 242
Description: Purified Polyclonal LIF antibody

LIF Antibody

1-CSB-PA004761
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  • 100ug
  • 50ug
Description: A polyclonal antibody against LIF. Recognizes LIF from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/20000

LIF Antibody

1-CSB-PA012928ESR2HU
  • Ask for price
  • Ask for price
  • 100ul
  • 50ul
Description: A polyclonal antibody against LIF. Recognizes LIF from Human. This antibody is Unconjugated. Tested in the following application: ELISA

LIF Antibody

1-CSB-PA198481
  • Ask for price
  • Ask for price
  • 100ul
  • 50ul
Description: A polyclonal antibody against LIF. Recognizes LIF from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:10000, IHC:1:25-1:100

LIF Antibody

GWB-MT498C 50ug Ask for price

LIF Antibody

F49998-0.08ML 0.08 ml
EUR 140.25
Description: LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface.

LIF Antibody

F49998-0.4ML 0.4 ml
EUR 322.15
Description: LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface.

LIF antibody

PAab09804 100 ug
EUR 463.2

LIF Antibody

R30639 100 ug
EUR 356.15
Description: LIF is a pleiotropic cytokine produced at the maternal-fetal interface which has been shown to play an essential role in implantation in mice. It is produced in high amounts by the human endometrium and the trophoblast itself, and its receptors are present on cytotrophoblast cells. LIF could thus play a role in modulating HLA-G production and immune tolerance at the maternal-fetal interface. The gene maps to 22q11-q12.2, between the Philadelphia translocation BCR gene and the breakpoint of the translocation in cell line GM2324 at 22q12.2.

LIF Antibody

R31467 100 ug
EUR 356.15
Description: LIF is a pleiotropic cytokine produced at the maternal-fetal interface which has been shown to play an essential role in implantation in mice. This gene is mapped to 22q11-q12.2, between the Philadelphia translocation BCR gene and the breakpoint of the translocation in cell line GM2324 at 22q12.2. LIF is produced in high amounts by the human endometrium and the trophoblast itself, and LIF receptors are present on cytotrophoblast cells. It could, thus, play a role in modulating HLA-G production and immune tolerance at the maternal-fetal interface.

LIF Antibody

R36251-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: Leukemia inhibitory factor

Recombinant Mouse Leukemia Inhibitory Factor/lIF

AP75318 1mg
EUR 3209

Recombinant Mouse Leukemia Inhibitory Factor/lIF

C690-10ug 10ug
EUR 175.2
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Mouse Leukemia Inhibitory Factor/lIF

C690-1mg 1mg
EUR 2739.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Mouse Leukemia Inhibitory Factor/lIF

C690-500ug 500ug
EUR 1935.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Mouse Leukemia Inhibitory Factor/lIF

C690-50ug 50ug
EUR 363.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

LIF Protein Vector (Mouse) (pPM-C-HA)

PV196580 500 ng
EUR 723.6

LIF Protein Vector (Mouse) (pPM-C-HA)

PV196584 500 ng
EUR 723.6

LIF

cyt-644 5µg
EUR 60
Description: Recombinant Human Leukemia Inhibitory Factor

LIF

E8ER1912-32 100ul
EUR 275
Description: Available in various conjugation types.

 

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